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pyrazole derivatives and 2H-chromene derivatives are presented in chapter four and
chapter five respectively. Moreover, an optimization study with different conditions was
provided in this chapters.
Chapter 6 provided a biological assessment of the recently synthesized compounds.
Here I have represented the molecular docking study of all synthesized compounds for
anticancer activity (chapter 2). All synthesized compounds are provided their
antibacterial activity and SAR studies (chapter 3 and chapter 4). The synthesized
compounds are tested using the agar well diffusion technique against bacterial and
fungal strains. The antioxidant activity of chapter 5’s derivatives is evaluated using DPPH
free radical scavenging activity.
Key words: Conventional and microwave reaction, One-pot multicomponent reaction,
Ultrasound irradiation, Sonochemistry, Green chemistry, 1,3,4-oxadiazole, 1,8-
naphthyridine, pyrano[2,3-c] pyrazole, 2H-chromene, DPPH, Anticancer activity,
Antimicrobial activity, Antioxidant activity
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