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Ph.D.
                                                                               (Engineering & Technology)
        DEVELOPMENT OF PREDICTIVE ANALYTICS MODEL FOR DISEASE
        PREDICTION USING MACHINE LEARNING TECHNIQUES

        Ph.D. Scholar : Chauhan Hetal Bhupendrasinh
        Research Supervisor : Dr. Kirit J. Modi



                                                                              Regi. No.: 17276341006
        Abstract :
        A  remarkable  amount  of  research  has  been  proceeding  to  apply  machine  learning
        techniques  to  produce  healthcare  solutions  due  to  availability,  adaptability  and
        advancement  of  cloud  and  web  technologies.    On  the  other  hand,  COVID19  diagnosis
        process in its current form is facing the problems of shortage of medical resources with
        high  growth  of  confirmed  cases  that  results  in  large  waiting  time  for  screening  of
        COVID19 patients. Increase in diagnosis time enhances the chances of cross infection.
        Essential requirement to stop the outbreak is early diagnosis of COVID19 patients. Even
        though  cases  are  under  control,  people  living  to  remote  places  cannot  get  timely
        treatment due to unavailability of specialized experts. Machine learning based predictive
        models can come up with the solution to the issues of COVID19 diagnosis by assisting in
        initial screening as well as helping experts in decision making.
        Researchers  used  machine  learning  classifiers  to  predict  COVID19  positivity.  We  also
        propose a framework to classify a sample with clinically assessed parameters, patient-
        reported symptoms, past medical histories into COVID19 positive or negative. Novelty of
        our  work  includes  the  method  to  find  optimal  subset  of  features  for  improved
        performance of classification. Results of experiments revel that a classifier trained with
        features  selected  by  the  proposed  method  got  better  accuracy  of  around  3%  to  12  %
        compared to a classifier trained on all the features in the dataset.

        Efforts have been applied to develop COVID19 prediction system using either of chest X-
        rays,  CT  scans  or  clinical  parameters.  Few  works  have  been  done  incorporating  multi-
        modal  inputs.  Most  approaches  developed  to  predict  disease  positivity  only  without
        predicting  disease  severity.  Predicting  severity  of  infection  is  important  in  resource
        management  and  reducing  mortality.  We  propose  reliable  multimodal  framework  to
        classify a sample into mild, moderate or severe class denoting infection severity. Sample
        includes text data (Patient details, co morbidities, blood parameters) and X-ray images.
        We  also  propose  AMSFmap  methodology  to  improve  image  classification  result.
        Experiment  results  concluded  that  incorporating  AMSFmap  in  existing  CNN  model
        results increase in accuracy of the model to around 4% to 9% and the proposed approach
        significantly outperformed existing approaches to classify COVID19 chest X-ray images.

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